Wayne State University, Detroit, USA.
Heart Fail Rev. 2009 Sep;14(3):135-41. doi: 10.1007/s10741-008-9100-3. Epub 2008 Aug 29.
Central apnea during sleep represents a manifestation of breathing instability in many clinical conditions of varied etiologies. Central apnea is the result of transient cessation of ventilatory motor output, which represents that inhibitory influences favoring instability predominate over excitatory influence favoring stable breathing. This article will review the determinants of central apnea, the specific features of CHF-related central apnea, and outline a management approach.
睡眠中的中枢性呼吸暂停是许多病因不同的临床情况下呼吸不稳定的一种表现。中枢性呼吸暂停是通气驱动输出短暂停止的结果,这表明有利于不稳定的抑制性影响超过了有利于稳定呼吸的兴奋性影响。本文将综述中枢性呼吸暂停的决定因素、心力衰竭相关中枢性呼吸暂停的特征,并概述管理方法。