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疾病、药物服用与道路交通事故责任:一项病例对照研究。

Diseases, consumption of medicines and responsibility for a road crash: a case-control study.

作者信息

Hours Martine, Fort Emmanuel, Charnay Pierrette, Bernard Marlène, Martin Jean Louis, Boisson Dominique, Sancho Pierre-Olivier, Laumon Bernard

机构信息

Epidemiological Research and Surveillance Unit in Transport Occupation and Environment, UMRT9405, INRETS/Université Lyon I/InVS, INRETS, F-69500 Bron, France.

出版信息

Accid Anal Prev. 2008 Sep;40(5):1789-96. doi: 10.1016/j.aap.2008.06.017. Epub 2008 Jul 21.

Abstract

UNLABELLED

The role of medical conditions in crashes is a topic of public debate. Some studies suggest that there has been a reduction in road traffic crashes subsequent to the medical restrictions introduced on drivers with medical deficiencies. As in today's society the car is an important factor for independence and socialization, it seems important to consider whether diseases or consumption of drugs increase the risk of causing a road crash in comparison to well-known major crash risk factors. A case-control study was conducted (733 injured drivers). The cases were subjects who were partly or totally responsible for their crash. The 304 controls were the non-responsible drivers. Diseases and medicine consumption were analyzed using logistic regression models. Cases were characterized by a higher percentage of young men. They were more frequently affected by fatigue, as were subjects who had consumed alcohol. A higher risk in subjects suffering from hypertension is observed (adjusted odds ratio [adjOR]=3.82; 95%CI=[1.42-10.24]). An association between antidepressant consumption and responsibility appeared (adjOR=3.61; 95%CI=[1.30-10.03]).

CONCLUSION

Medical factors associated with responsibility were arterial hypertension and antidepressant consumption. Other medical conditions do not seem to play a preponderant role comparing to individual behaviours.

摘要

未标注

医疗状况在交通事故中所起的作用是一个公众辩论的话题。一些研究表明,对有医疗缺陷的驾驶员实施医疗限制后,道路交通事故有所减少。在当今社会,汽车是实现独立和社交的重要因素,因此,与众所周知的主要事故风险因素相比,考虑疾病或药物使用是否会增加引发道路交通事故的风险似乎很重要。开展了一项病例对照研究(733名受伤驾驶员)。病例组为对其事故负有部分或全部责任的受试者。304名对照组为无责任的驾驶员。使用逻辑回归模型分析疾病和药物使用情况。病例组的特点是年轻男性比例较高。他们更频繁地受到疲劳影响,饮酒者也是如此。观察到高血压患者的风险更高(调整后的优势比[adjOR]=3.82;95%置信区间[CI]=[1.42 - 10.24])。抗抑郁药的使用与事故责任之间存在关联(adjOR=3.61;95%CI=[1.30 - 10.03])。

结论

与事故责任相关的医疗因素是动脉高血压和抗抑郁药的使用。与个人行为相比,其他医疗状况似乎并未起到主要作用。

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