Nelson Kyle A, Meadows Lisa, Yan Yan, Schootman Mario, Strunk Robert C
Division of Emergency Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
J Pediatr. 2009 Jan;154(1):111-5. doi: 10.1016/j.jpeds.2008.07.017. Epub 2008 Aug 29.
We reexamined asthma prevalence in urban public elementary school children after 12 years, during which time poverty had worsened.
We surveyed 152 children in 1992 and 331 in 2004 attending fourth- and fifth-grade classrooms in a low-income area of St. Louis, Missouri. Prevalences of phenotypes (current asthma, previous diagnosis without current asthma, and frequent wheezing without diagnosis) were based on standard published questions. We assessed age, sex, percentage below poverty level, and asthma experience (household member with asthma; friend, relative, or neighbor with asthma; or ever having seen someone have an attack).
Prevalences were similar in 1992 and 2004 for current asthma (18% and 20%) and frequent wheezing without diagnosis (24% and 26%), despite higher 2004 percentage below poverty level (40% vs 18%). Prevalences of phenotypes were not associated with demographics or percentage below poverty level but were associated with asthma experience. In multivariate analysis, current asthma was associated with household member with asthma and ever having seen someone have an attack, and previous diagnosis was associated with household member with asthma.
For these fourth- and fifth-grade urban public school children, self-reported asthma prevalence was similar after 12 years despite worsening poverty.
我们在时隔12年之后重新调查了城市公立小学儿童的哮喘患病率，在此期间贫困状况有所恶化。
我们于1992年对152名儿童以及2004年对331名在密苏里州圣路易斯市低收入地区就读四、五年级的儿童进行了调查。根据已发表的标准问题确定各表型（当前哮喘、既往诊断为哮喘但目前未发病、经常喘息但未确诊）的患病率。我们评估了年龄、性别、贫困线以下人口百分比以及哮喘经历（家庭成员患有哮喘；朋友、亲戚或邻居患有哮喘；或曾目睹他人发作）。
尽管2004年贫困线以下人口百分比更高（40%对18%），但1992年和2004年当前哮喘（分别为18%和20%）以及经常喘息但未确诊（分别为24%和26%）的患病率相似。各表型的患病率与人口统计学特征或贫困线以下人口百分比无关，但与哮喘经历有关。在多变量分析中，当前哮喘与家庭成员患有哮喘以及曾目睹他人发作有关，既往诊断为哮喘与家庭成员患有哮喘有关。
对于这些四、五年级的城市公立学校儿童，尽管贫困状况恶化，但12年后自我报告的哮喘患病率相似。
