Epidemiology Unit, Victorian Infectious Diseases Reference Laboratory, Australia.
Vaccine. 2010 Mar 16;28(13):2532-8. doi: 10.1016/j.vaccine.2010.01.036. Epub 2010 Jan 29.
Varicella vaccine was licensed in Australia in 1999 and publicly funded in 2005. We examined trends in varicella and zoster hospitalisations and community consultations in Victoria during periods of no vaccine, private availability of vaccine and funded vaccination. Varicella hospitalisation rates declined 7% per year (95% CI 5-9%) from 2000 to 2007, predominately in children under five (12% per year, 95% CI 9-16%). A similar decline was seen in community data. The zoster hospitalisation rate increased from 1998 to 2007 (5% per year, 95% CI 3-6%), before introduction of varicella vaccine. Among those aged 80 and over the hospitalisation rate increased 5% per year (95% CI 3-7%) from 1998 to 2007. Zoster increased in community data from 2001.
水痘疫苗于 1999 年在澳大利亚获得许可,并于 2005 年获得公共资助。我们在没有疫苗、疫苗私人供应和疫苗资助接种的时期,检查了维多利亚州水痘和带状疱疹住院和社区咨询的趋势。从 2000 年到 2007 年,水痘住院率每年下降 7%(95%CI 5-9%),主要是五岁以下儿童(每年 12%,95%CI 9-16%)。社区数据也出现了类似的下降。带状疱疹的住院率从 1998 年到 2007 年上升(每年 5%,95%CI 3-6%),在水痘疫苗推出之前。在 80 岁及以上的人群中,从 1998 年到 2007 年,住院率每年增加 5%(95%CI 3-7%)。带状疱疹在社区数据中的发病率从 2001 年开始上升。