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疑似泌尿系统癌症转诊的“两周等待”规则——迫切需要完善标准。

The '2-week wait' rule for referrals for suspected urological cancers--urgent need for refinement of criteria.

作者信息

Hawary Amr M, Warburton Hazel E, Brough Richard J, Collins Gerald N, Brown Stephen C, O'Reilly Patrick H, Adeyoju Adebanji Ab

机构信息

Department of Urology, Stepping Hill Hospital, Stockport, UK.

出版信息

Ann R Coll Surg Engl. 2008 Sep;90(6):517-22. doi: 10.1308/003588408X301082.

Abstract

INTRODUCTION

All NHS-suspected cancers should be seen within 2 weeks of referral and are referred under government guidelines (Health Service Circular 205; HSC 205). This policy will be subject to review in 2009. Review is vital to allow the appropriate detection of malignancy without overburdening the premium clinic slots with the healthy.

PATIENTS AND METHODS

A total of 170 consecutive patients were referred from January-June 2005. Referral details, patient information, events and time to diagnosis were recorded.

RESULTS

Of these 170 patients, 143 were suitable for analysis. Forty-three patients (30%) were referred with frank haematuria, of whom 30% had bladder cancer. Nine percent of patients (n = 13) had microscopic haematuria none of whom had cancer. A quarter of the patients (n = 35) were referred with suspected testis cancer but none had cancer. Forty-one patients were referred with serum prostate-specific antigen (PSA) elevation; 18 cancers were detected in this group. Ten men had PSA values greater than 50 ng/ml. Only two cancers were suitable for radical prostatectomy. No cancer was found in patients less than 50 years of age.

CONCLUSIONS

A high cancer incidence was found (27.9%), the majority of which was bladder cancer or advanced prostate cancer. Out of the 143 patients, no malignancy was diagnosed in any patient less than 50 years of age, no malignancy was diagnosed in any of the microscopic haematuria group and there was no cancer diagnosed in the group of patients referred with scrotal swellings. We suggest that some guidelines are leading to referral of patients with low cancer risk. When the HSC 205 is revised in 2009, we hope studies such as ours are taken into consideration in order to improve resource utilisation.

摘要

引言

所有疑似国民保健制度(NHS)癌症的患者应在转诊后2周内就诊,并根据政府指南(《卫生服务通告205》;HSC 205)进行转诊。该政策将于2009年接受审查。审查至关重要,以便在不过度占用高级诊所时段接待健康人群的情况下,实现对恶性肿瘤的适当检测。

患者与方法

2005年1月至6月期间,共连续转诊了170例患者。记录了转诊细节、患者信息、事件及诊断时间。

结果

在这170例患者中,143例适合进行分析。43例(30%)患者因肉眼血尿转诊,其中30%患有膀胱癌。9%的患者(n = 13)有镜下血尿,但均未患癌症。四分之一的患者(n = 35)因疑似睾丸癌转诊,但均未患癌症。41例患者因血清前列腺特异性抗原(PSA)升高转诊;该组中检测出18例癌症。10名男性的PSA值大于50 ng/ml。只有2例癌症适合进行根治性前列腺切除术。50岁以下患者未发现癌症。

结论

发现癌症发病率较高(27.9%),其中大多数为膀胱癌或晚期前列腺癌。在143例患者中,50岁以下患者均未诊断出恶性肿瘤,镜下血尿组患者均未诊断出恶性肿瘤,因阴囊肿胀转诊的患者组也未诊断出癌症。我们认为,一些指南导致了癌症风险较低的患者被转诊。当2009年修订HSC 205时,我们希望能考虑到我们这样的研究,以提高资源利用效率。

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