Schindler A, Borghi E, Tiddia C, Ginocchio D, Felisati G, Ottaviani F
University of Milan, Department of Clinical Sciences L. Sacco, Via GB Grassi 74, 20157 Milano, Italy.
Rev Laryngol Otol Rhinol (Bord). 2008;129(2):97-100.
Oropharyngeal dysphagia is a common symptom in patients with head and neck tumours. The MD Anderson Dysphagia Inventory (MDADI) is a questionnaire currently used in North America for the assessment of dysphagia-related disability in patients with head and neck cancer. The aim of the study is to analyze reliability and clinical validity of the Italian MDADI.
48 persons with no history of dysphagia and 50 head and neck cancer patients with a chronic and stable dysphagia have been included in the study. Each subject completed alone the Italian MDADI twice with a week interval between the two questionnaire completion. Intra-subject reliability was analyzed through Pearson test in both groups of subjects. Clinical validity was calculated through the non parametric Mann Whitney test of the first MDADI assessment in both groups.
Internal consistency and test-retest reliability were high for each MDADI subscale in subjects without dysphagia as well as in those with dysphagia. The difference between MDADI values in subjects with and without dysphagia was significant for each subscale.
The Italian MDADI is reliable and clinically valid. The application of the MDADI is recommended in clinical practice as well as in descriptive, outcome and efficacy research.
口咽吞咽困难是头颈部肿瘤患者的常见症状。MD安德森吞咽困难量表(MDADI)是北美目前用于评估头颈部癌症患者吞咽困难相关残疾情况的一份问卷。本研究旨在分析意大利版MDADI的信度和临床效度。
本研究纳入了48例无吞咽困难病史的人和50例患有慢性稳定型吞咽困难的头颈部癌症患者。每位受试者独立完成意大利版MDADI问卷两次,两次问卷填写间隔一周。通过Pearson检验分析两组受试者的组内信度。通过两组首次MDADI评估的非参数Mann Whitney检验计算临床效度。
在无吞咽困难的受试者以及有吞咽困难的受试者中,每个MDADI子量表的内部一致性和重测信度都很高。有吞咽困难和无吞咽困难受试者的MDADI值在每个子量表上的差异都很显著。
意大利版MDADI可靠且具有临床效度。建议在临床实践以及描述性、结局和疗效研究中应用MDADI。