Takahashi Takeo, Hondo Mikito, Nishimura Keiichiro, Kitani Akira, Yamano Takafumi, Yanagita Hisami, Osada Hisato, Shinbo Munefumi, Honda Norinari
Department of Radiology, Saitama Medical Center, Saitama Medical University, Kawagoe, 350-8550, Japan.
Radiat Med. 2008 Aug;26(7):396-401. doi: 10.1007/s11604-008-0248-5. Epub 2008 Sep 4.
The importance of the quality of life (QOL) and mental condition of patients being treated for cancer is now recognized. In this study, we evaluated QOL and mental condition in patients with cancer before and after radiotherapy.
The subjects were 170 patients who had undergone radiotherapy. The examination of QOL was performed using the quality of life questionnaire for cancer patients treated with anticancer drugs (QOL-ACD), and mental condition (anxiety and depression) was examined using the hospital anxiety and depression scale (HADS). These examinations were performed at the start of radiotherapy and immediately after radiotherapy.
The QOL score was slightly higher in all patients after the completion of radiotherapy than before the start of radiotherapy. In the palliative radiotherapy group, QOL score was significantly improved by treatment. Anxiety and depression were improved after radiotherapy. There was a correlation between the degrees of improvement of the HADS and QOL score.
We could treat cancer patients by radiotherapy without reducing their QOL, and improvement in QOL was significant in the palliative radiotherapy group. Mental condition was also improved after radiotherapy.
目前已认识到癌症患者生活质量(QOL)和心理状况的重要性。在本研究中,我们评估了癌症患者放疗前后的生活质量和心理状况。
研究对象为170例接受过放疗的患者。使用抗癌药物治疗癌症患者的生活质量问卷(QOL-ACD)进行生活质量检查,并使用医院焦虑抑郁量表(HADS)检查心理状况(焦虑和抑郁)。这些检查在放疗开始时和放疗结束后立即进行。
所有患者放疗结束后的生活质量评分略高于放疗开始前。在姑息性放疗组中,治疗后生活质量评分显著提高。放疗后焦虑和抑郁症状有所改善。HADS改善程度与生活质量评分之间存在相关性。
我们可以通过放疗治疗癌症患者而不降低其生活质量,并且在姑息性放疗组中生活质量改善显著。放疗后心理状况也有所改善。