Picault J P, Guittet M, Bennejean G
Ministere de l'Agriculture, Direction de la Qualite, Services Veterinaires Laboratoire National de Pathologie Aviaire, Ploufragan, France.
Avian Pathol. 1982;11(1):39-48. doi: 10.1080/03079458208436080.
The safety spreading properties and potency of three commercial vaccines used for the prevention of avian infectious laryngotracheitis have been studied. Results showed that the different strains are not safe when administrated by the intratracheal route; when administrated by the ocular route, the vaccinal reaction was limited to a transitory conjunctivitis. Under certain conditions of proximity the vaccine viruses spread from vaccinated to contact chickens. Good protection was afforded by vaccination by ocular route, but not when the vaccines were administrated in the drinking water. There was concordance between the level of protection following vaccination and the neutralising antibodies titres. The protection was relatively short-lived: 10 to 15 weeks after vaccination, half of challenged birds showed clinical signs of the disease, and 20 weeks after vaccination all of them were sick.
对三种用于预防禽传染性喉气管炎的商用疫苗的安全性传播特性和效力进行了研究。结果表明，不同毒株经气管内途径接种时不安全；经眼途径接种时，疫苗反应仅限于短暂的结膜炎。在一定的接近条件下，疫苗病毒从接种鸡传播到接触鸡。经眼途径接种疫苗可提供良好的保护，但通过饮水接种疫苗则不能。接种后的保护水平与中和抗体滴度之间存在一致性。保护作用相对短暂：接种疫苗10至15周后，一半受攻击的鸡出现该病的临床症状，接种疫苗20周后，所有鸡都发病。
