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直肠癌前切除术后回肠袢式造口的适时关闭。

Timely closure of loop ileostomy following anterior resection for rectal cancer.

作者信息

Chand M, Nash G F, Talbot R W

机构信息

Southampton General Hospital, Southampton, Hampshire, UK.

出版信息

Eur J Cancer Care (Engl). 2008 Nov;17(6):611-5. doi: 10.1111/j.1365-2354.2008.00972.x. Epub 2008 Sep 3.

Abstract

The implications of constructing a temporary ileostomy as part of the primary surgery for some rectal cancers must not be underestimated and many patients are particularly keen to have their stoma closed as early as possible. Currently, there are no set protocols in place which determine when this should take place, meaning that stoma reversal can be extremely variable between hospitals in the UK. We have created a policy to give patients a provisional date for ileostomy closure at discharge from primary surgery, which takes into account any necessary adjuvant treatment. We compared time to closure of ileostomy between two adjacent centres that share common stoma-care and oncology teams to see what benefit this policy provides. Patients were recruited over a 2-year period from 2005 to 2007 from two adjacent centres. Centre 1 had a policy to provide patients with a provisional date for closure of their ileostomy. The notes were studied retrospectively to determine time to closure of the ileostomy and reasons for any delays in closure. A total of 107 patients fulfilled the inclusion criteria, of which 83 patients (72%) had their stomas closed. Thirty patients had their stomas closed within 12 weeks (37%) - more than 67% (23/34) in centre 1 against 15% (7/48) in centre 2. At 1 year, all patients in centre 1 had their ileostomy closed, while 10% (5/48) were still waiting in centre 2. The mean time to closure was 13.47 and 25.25 weeks for centres 1 and 2 respectively -P-value < 0.0001. Offering patients a date for ileostomy closure at discharge from their primary resection results in the majority of stomas being closed within 12 weeks. For those patients who are to undergo adjuvant chemotherapy, we aim to perform this surgery in between the second and third cycles of treatment.

摘要

作为某些直肠癌初次手术一部分而构建临时回肠造口术的影响绝不可被低估,许多患者尤其渴望尽早关闭造口。目前,尚无既定方案来确定何时进行造口关闭,这意味着在英国各医院之间,造口还纳手术的差异可能极大。我们制定了一项政策,在初次手术出院时为患者提供回肠造口关闭的暂定日期,该日期会考虑到任何必要的辅助治疗。我们比较了两个共用造口护理和肿瘤学团队的相邻中心之间回肠造口关闭的时间,以了解该政策带来了哪些益处。在2005年至2007年的两年期间,从两个相邻中心招募了患者。中心1有一项政策,即向患者提供回肠造口关闭的暂定日期。对病历进行回顾性研究,以确定回肠造口关闭的时间以及关闭延迟的原因。共有107名患者符合纳入标准,其中83名患者(72%)的造口被关闭。30名患者在12周内关闭了造口(37%)——中心1超过67%(23/34),而中心2为15%(7/48)。1年后,中心1的所有患者回肠造口均已关闭,而中心2仍有10%(5/48)的患者在等待。中心1和中心2的平均关闭时间分别为13.47周和25.25周——P值<0.0001。在初次切除术后出院时为患者提供回肠造口关闭日期,会使大多数造口在12周内关闭。对于那些要接受辅助化疗的患者,我们的目标是在治疗的第二和第三个周期之间进行这项手术。

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