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生物活性硅酸钙陶瓷及涂层

Bioactive calcium silicate ceramics and coatings.

作者信息

Liu Xuanyong, Morra Marco, Carpi Angelo, Li Baoe

机构信息

Shanghai Institute of Ceramics, Chinese Academy of Science, 1295 Dingxi Road, Shanghai 200050, China.

出版信息

Biomed Pharmacother. 2008 Oct;62(8):526-9. doi: 10.1016/j.biopha.2008.07.051. Epub 2008 Aug 8.

Abstract

CaO-SiO2 based ceramics have been regarded as potential candidates for artificial bone due to their excellent bone bioactivity and biocompatibility. However, they cannot be used as implants under a heavy load because of their poor mechanical properties, in particular low fracture toughness. Plasma spraying CaO-SiO2 based ceramic coatings onto titanium alloys can expand their application to the hard tissue replacement under a heavy load. Plasma sprayed wollastonite, dicalcium silicate and diopside coatings have excellent bone bioactivity and high bonding strength to titanium alloys. It is possible that these plasma sprayed CaO-SiO2 based ceramic coatings will be applied in clinic after they are widely and systematically researched.

摘要

由于具有优异的骨生物活性和生物相容性,CaO-SiO₂基陶瓷被视为人工骨的潜在候选材料。然而,由于其力学性能较差,特别是断裂韧性低,它们不能在重载条件下用作植入物。在钛合金上等离子喷涂CaO-SiO₂基陶瓷涂层可以将其应用扩展到重载下的硬组织替代。等离子喷涂的硅灰石、硅酸二钙和透辉石涂层具有优异的骨生物活性和与钛合金的高结合强度。这些等离子喷涂的CaO-SiO₂基陶瓷涂层在经过广泛而系统的研究后有可能应用于临床。

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