Primathena Indra, Nurdin Denny, Hermawan Hendra, Cahyanto Arief
Department of Conservative Dentistry, Faculty of Dentistry, Universitas Padjadjaran, Bandung 40132, West Java, Indonesia.
Department of Mining, Metallurgical and Materials Engineering, Faculty of Sciences and Engineering, Université Laval, Quebec City, QC G1V0A6, Canada.
Materials (Basel). 2021 Jan 15;14(2):417. doi: 10.3390/ma14020417.
Mineral trioxide aggregate (MTA) is an ideal yet costly endodontic sealer material. Tricalcium silicate-white Portland cement (TS-WPC) seems to have similar characteristics to those of MTA. This work aims to characterize a modified TS-WPC and evaluate its antibacterial properties as a potential endodontic sealer material. The modified TS-WPC was synthesized from a 4:1 mixture of sterilized Indocement TS-WPC and bismuth trioxide using a simple solution method with 99.9% isopropanol. The mixture was stirred until it was homogenous, centrifuged, and dried. The material was then characterized using infrared spectroscopy, X-ray diffraction, and electron microscopy and subjected to antibacterial evaluation against using a Mueller-Hinton agar inhibition test. The results showed that the material was characterized by main functional groups of hydroxyls, silicate, bismuth trioxide, and tricalcium silicate, like those of a commercial MTA-based sealer, both tested after hydration. Modified TS-WPC before hydration showed similar powder morphology and size to the commercial one, indicating the ease of manipulation. Both materials exhibited antibacterial activity due to calcium dihydroxide's ability to absorb carbon dioxide, which is essential for the anaerobic , with minimum inhibitory effect and bactericidal concentrations of 12,500 ppm and 25,000 ppm, respectively. The modified TS-WPC has the potential to become a cost-effective alternative endodontic sealer material.
矿物三氧化物凝聚体（MTA）是一种理想但昂贵的牙髓封闭剂材料。硅酸三钙 - 白色波特兰水泥（TS - WPC）似乎具有与MTA相似的特性。这项工作旨在对一种改性TS - WPC进行表征，并评估其作为潜在牙髓封闭剂材料的抗菌性能。改性TS - WPC是由灭菌的印度水泥TS - WPC和三氧化二铋按4:1的混合物，采用简单的溶液法，使用99.9%的异丙醇合成的。将混合物搅拌至均匀，离心并干燥。然后使用红外光谱、X射线衍射和电子显微镜对该材料进行表征，并通过穆勒 - 欣顿琼脂抑制试验对其进行抗菌评估。结果表明，该材料的特征在于羟基、硅酸盐、三氧化二铋和硅酸三钙的主要官能团，与一种市售的基于MTA的封闭剂在水化后测试的情况类似。水化前的改性TS - WPC显示出与市售产品相似的粉末形态和尺寸，表明其易于操作。由于氢氧化钙吸收二氧化碳的能力，这两种材料都表现出抗菌活性，而二氧化碳对于厌氧菌至关重要，其最小抑菌浓度和杀菌浓度分别为12,500 ppm和25,000 ppm。改性TS - WPC有潜力成为一种经济高效的替代牙髓封闭剂材料。
