An enzyme assembly line.
作者信息
Smith Janet L, Sherman David H
机构信息
Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
出版信息
Science. 2008 Sep 5;321(5894):1304-5. doi: 10.1126/science.1163785.
Abstract
摘要
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本文引用的文献
1
The crystal structure of a mammalian fatty acid synthase.一种哺乳动物脂肪酸合酶的晶体结构。
Science. 2008 Sep 5;321(5894):1315-22. doi: 10.1126/science.1161269.
2
Crystal structure of the termination module of a nonribosomal peptide synthetase.非核糖体肽合成酶终止模块的晶体结构
Science. 2008 Aug 1;321(5889):659-63. doi: 10.1126/science.1159850. Epub 2008 Jun 26.
3
The evolution of gene collectives: How natural selection drives chemical innovation.基因集合体的进化：自然选择如何驱动化学创新。
Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4601-8. doi: 10.1073/pnas.0709132105. Epub 2008 Jan 23.
4
GNAT-like strategy for polyketide chain initiation.聚酮链起始的类GNAT策略。
Science. 2007 Nov 9;318(5852):970-4. doi: 10.1126/science.1148790.
5
The origins of specificity in polyketide synthase protein interactions.聚酮合酶蛋白相互作用特异性的起源。
PLoS Comput Biol. 2007 Sep;3(9):1827-35. doi: 10.1371/journal.pcbi.0030186.
6
Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids.用于复杂分枝杆菌脂质生物合成的多功能聚酮化合物酶机制。
Nat Prod Rep. 2007 Apr;24(2):267-77. doi: 10.1039/b616817p. Epub 2007 Feb 28.
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Escherichia coli induces DNA double-strand breaks in eukaryotic cells.大肠杆菌可诱导真核细胞中的DNA双链断裂。
Science. 2006 Aug 11;313(5788):848-51. doi: 10.1126/science.1127059.
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The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.6-脱氧红霉内酯B合酶194 kDa同二聚体片段的2.7埃晶体结构。
Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11124-9. doi: 10.1073/pnas.0601924103. Epub 2006 Jul 14.
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The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases.酮还原酶的结构决定了模块化聚酮合酶的β-碳加工酶的组织方式。
Structure. 2006 Apr;14(4):737-48. doi: 10.1016/j.str.2006.01.009. Epub 2006 Mar 23.
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Architecture of a fungal fatty acid synthase at 5 A resolution.5埃分辨率下真菌脂肪酸合酶的结构
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