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将精神分裂症描述为一种遗传性疾病所带来的污名化影响。

The stigmatising implications of presenting schizophrenia as a genetic disease.

作者信息

Bennett Laura, Thirlaway Kathryn, Murray Alexandra J

机构信息

Institute of Medical Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XW, UK.

出版信息

J Genet Couns. 2008 Dec;17(6):550-9. doi: 10.1007/s10897-008-9178-8. Epub 2008 Sep 5.

Abstract

This study aimed to investigate the hypothesis that belief in a genetic aetiology of schizophrenia will increase the stigma associated with the disorder. Levels of five potentially stigmatising attitudes were compared in two groups of participants who had read a vignette describing an individual who has schizophrenia. In one group the disorder was explained as being caused by 'genetic' factors, and in the other by 'environmental' factors. This study found that three of the five potentially stigmatising attitudes measured were increased when participants read a vignette with a genetic causation rather than an environmental causation. Firstly, genetic attributions increased levels of associative stigma towards close relatives (p < 0.001). Secondly, participants viewed recovery as less likely when genetic factors were implicated as causative (p < 0.001). Finally, there was also an increased perception of the character's "dangerousness" when the condition was explained by genetic factors (p < 0.05). Contrary to previous research was the finding that perceived aetiology had no effect on participant's desire for social distance from an affected individual. Neither did perceived aetiology influence beliefs about moral accountability. The implications of these findings suggest that genetic counsellors and other health professionals, who are providing genetic information to those affected by schizophrenia should be aware of the possibility that a genetic explanation of schizophrenia could increase potentially stigmatising attitudes towards their clients and their clients' families. It is also possible that individuals with a diagnosis of schizophrenia may themselves form deterministic interpretations of the genetic information they receive and subsequently be less likely to adopt behavioural advice or adhere to treatment. Counsellors and health professionals should strive to present information in a balanced manner, ensuring recipients understand the multi-factorial causes of the disease.

摘要

本研究旨在调查一种假设,即认为精神分裂症具有遗传病因会增加与该疾病相关的污名化。在两组阅读了描述一名精神分裂症患者的短文的参与者中,比较了五种潜在污名化态度的水平。在一组中,该疾病被解释为由“遗传”因素引起,而在另一组中被解释为由“环境”因素引起。本研究发现,当参与者阅读具有遗传病因而非环境病因的短文时,所测量的五种潜在污名化态度中有三种会增加。首先,遗传归因增加了对近亲的联想污名水平(p<0.001)。其次,当遗传因素被认为是病因时,参与者认为康复的可能性较小(p<0.001)。最后,当用遗传因素解释病情时,对该角色“危险性”的认知也有所增加(p<0.05)。与先前的研究相反的是,病因认知对参与者与受影响个体保持社交距离的意愿没有影响。病因认知也没有影响对道德责任的看法。这些发现的意义表明,向精神分裂症患者提供遗传信息的遗传咨询师和其他健康专业人员应意识到,对精神分裂症的遗传解释可能会增加对其客户及其客户家庭的潜在污名化态度。也有可能被诊断为精神分裂症的个体自己会对他们收到的遗传信息形成决定论的解释,随后不太可能接受行为建议或坚持治疗。咨询师和健康专业人员应努力以平衡的方式呈现信息,确保接受者了解该疾病的多因素病因。

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