Stevens R H, Smith D D, Osborne J W, Oberley L W
J Natl Cancer Inst. 1976 Jul;57(1):43-5. doi: 10.1093/jnci/57.1.43.
X-ray-induced adenocarcinomas in the small bowels of outbred Lewis Brown Norway and Holtzman rats contained significantly lower concentrations of adenosine 3',5'-cyclic monophosphate than did normal rat intestinal tissue. No significant differences were observed between the intracellular concentrations of the nucleotide in the normal rat small bowel and those occurring in normal-appearing intestinal tissue exposed to tumor induction conditions.
在远交系Lewis Brown Norway和Holtzman大鼠的小肠中，X射线诱导产生的腺癌组织所含的3',5'-环磷酸腺苷浓度，显著低于正常大鼠的肠道组织。在正常大鼠小肠中的核苷酸细胞内浓度，与处于肿瘤诱导条件下看似正常的肠道组织中的核苷酸细胞内浓度之间，未观察到显著差异。
