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Lymphocyte cytotoxicity in X-irradiation-induced adenocarcinoma of the rat small bowel. I. Measurement of target cell destruction by release of radioiodinated membrane proteins: brief communication.

作者信息

Stevens R H, Brooks G P, Osborne J W, Englund C W, White D W

出版信息

J Natl Cancer Inst. 1977 Oct;59(4):1315-9. doi: 10.1093/jnci/59.4.1315.

DOI:10.1093/jnci/59.4.1315
PMID:904002
Abstract

A cell-mediated immune response as denoted by lymphocyte cytotoxicity was detected in Holtzman rats with X-irradiation-induced adenocarcinomas of the small bowel. Cytotoxicity was measured by target cell destruction as determined by release of intracellular 51Cr or radioiodinated (125I) membrane proteins. The radioiodination assay possessed an important advantage over the 51Cr technique in that the radiolabel was spontaneously lost slowly, thus permitting long-term studies.

摘要

相似文献

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Lymphocyte cytotoxicity in X-irradiation-induced adenocarcinoma of the rat small bowel. I. Measurement of target cell destruction by release of radioiodinated membrane proteins: brief communication.
J Natl Cancer Inst. 1977 Oct;59(4):1315-9. doi: 10.1093/jnci/59.4.1315.
2
Lymphocyte cytotoxicity in the X-irradiation induced rat small bowel adenocarcinoma. II. Presence of cytotoxic lymphocytes in irradiated animals.X射线诱导的大鼠小肠腺癌中的淋巴细胞细胞毒性。II. 受辐照动物中细胞毒性淋巴细胞的存在
Immunol Commun. 1978;7(3):281-93. doi: 10.3109/08820137809025473.
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Lymphocyte cytotoxicity in X-irradiation induced rat small bowel adenocarcinoma. IV. Activation of cellular immunity by X irradiation.X射线诱导大鼠小肠腺癌中的淋巴细胞细胞毒性。IV. X射线对细胞免疫的激活作用。
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