Ghouri Nazim, Hippisley-Cox Julia, Newton John, Sheikh Aziz
Ayr Hospital, UK.
J R Soc Med. 2008 Sep;101(9):466-72. doi: 10.1258/jrsm.2008.080096.
To investigate recent trends in the recorded incidence, lifetime prevalence and prescribing of symptom relief medication for allergic rhinitis in England.
Analysis of primary healthcare datasets.
The UK prevalence of allergic rhinitis has increased very significantly over recent decades. Analysis of primary healthcare datasets offers the possibility to advance understanding about the changing epidemiology and management of allergic rhinitis. QRESEARCH is one of the world's largest national aggregated health databases containing the records of over nine million patients. We extracted data on all patients with a recorded diagnosis of allergic rhinitis and calculated annual age-sex standardized incidence and lifetime period prevalence rates for each year from 2001-2005. We also analysed prescribing trends for antihistamines and drugs used in nasal allergy in those with a recorded diagnosis of allergic rhinitis.
Age-sex standardized incidence, lifetime prevalence rates and prescribing trends for symptom relief medication for allergic rhinitis in England.
The age-sex standardized incidence of allergic rhinitis was 5.57 per 1000 person-years in 2001 and increased by 33.0% to 7.41 per 1000 person-years in 2005 (P<0.001). Lifetime age-sex standardized prevalence of a recorded diagnosis of allergic rhinitis increased by 43.2% from 46.35 per 1000 in 2001 to 66.37 per 1000 in 2005 (P<0.001). Over this period a 41.7% overall increase in prescriptions for antihistamines and drugs used in nasal allergy was observed (antihistamines 45.5%, drugs used in nasal allergies 35.5%).
Recorded incidence and lifetime prevalence of allergic rhinitis have increased substantially in recent years. A similar increase in prescriptions for antihistamines and drugs used in nasal allergy in patients with allergic rhinitis is also observed.
调查英格兰地区变应性鼻炎记录发病率、终生患病率及缓解症状药物处方的近期趋势。
对基层医疗数据集进行分析。
近几十年来，英国变应性鼻炎的患病率显著上升。对基层医疗数据集进行分析有助于加深对变应性鼻炎流行病学变化及管理的理解。QRESEARCH是世界上最大的国家综合健康数据库之一，包含900多万患者的记录。我们提取了所有记录诊断为变应性鼻炎患者的数据，并计算了2001年至2005年每年的年龄性别标准化发病率和终生患病率。我们还分析了记录诊断为变应性鼻炎患者的抗组胺药和鼻用变应性疾病药物的处方趋势。
英格兰地区变应性鼻炎缓解症状药物的年龄性别标准化发病率、终生患病率及处方趋势。
2001年变应性鼻炎的年龄性别标准化发病率为每1000人年5.57例，到2005年增加了33.0%，达到每1000人年7.41例（P<0.001）。记录诊断为变应性鼻炎的终生年龄性别标准化患病率从2001年的每1000人46.35例增加了43.2%，至2005年的每1000人66.37例（P<0.001）。在此期间，抗组胺药和鼻用变应性疾病药物的处方总量增加了41.7%（抗组胺药增加45.5%，鼻用变应性疾病药物增加35.5%）。
近年来，变应性鼻炎的记录发病率和终生患病率大幅上升。变应性鼻炎患者中抗组胺药和鼻用变应性疾病药物的处方量也有类似增加。
