Weissleder H, Pfannenstiel P, Peters P E
Lymphology. 1976 Sep;9(3):122-6.
Endolymphatic radiotherapy with 4 mCi32P tri-n-octylphosphate and 1 mCi 131 I triolein LIPIODOL UF has been performed in 75 patients suffering from malignant melanoma of the lower extremity. On the average, 13.3% of the radioactive substance remains in the syringes and connecting tubes. In most patients the radioactive material available for therapeutic irradiation is further reduced due to contamination of operation sheets and swabs (mean: 15.3%). There is, however, still sufficient radioactivity remaining for effective internal irradiation of the lymph nodes. The average radiation dose absorbed by the lymphatic tissue is 90.998 rad. The method is limited by the hazard of radiation damage to the lungs. Almost 80% of these patients had detectable concentrations of radioactivity in the lung fields. The average radiation dose was found to be 299 rad. So far radiation induced fibrosis has bot been observed in this series.
已对75例下肢恶性黑色素瘤患者进行了用4毫居里32P磷酸三正辛酯和1毫居里131I三油酸甘油酯超液化碘油进行的内淋巴放疗。平均而言，13.3%的放射性物质残留在注射器和连接管中。在大多数患者中，由于手术单和拭子的污染，可用于治疗性照射的放射性物质进一步减少（平均：15.3%）。然而，仍有足够的放射性剩余用于对淋巴结进行有效的内照射。淋巴组织吸收的平均辐射剂量为90.998拉德。该方法受到肺部辐射损伤风险的限制。这些患者中近80%在肺野中可检测到放射性浓度。发现平均辐射剂量为299拉德。到目前为止，在该系列中尚未观察到放射性纤维化。
