Gur David, Rockette Howard E
Department of Radiology, School of Medicine, University of Pittsburgh, 3362 Fifth Avenue, Pittsburgh, PA 15261-3180, USA.
Acad Radiol. 2008 Oct;15(10):1312-5. doi: 10.1016/j.acra.2008.05.006.
As use of free response receiver-operating characteristic (FROC) curves gains more acceptance for quantitatively assessing the performance of diagnostic systems, it is important that the experimentalist understands the possible role of this approach as one of the experimental design paradigms that are available to him or her among all other approaches as well as some of the issues associated with FROC type studies. In a number of experimental scenarios, the FROC paradigm and associated analytical tools have theoretical and practical advantages over both the binary and the ROC approaches to performance assessments of diagnostic systems, but it also has some limitations related to experimental design, data analyses, clinical relevance, and complexity in the interpretation of the results. These issues are rarely discussed and are the focus of this work.
随着自由反应接收者操作特征（FROC）曲线在定量评估诊断系统性能方面越来越被接受，实验者了解这种方法作为其可采用的实验设计范式之一在所有其他方法中的可能作用以及与FROC类型研究相关的一些问题非常重要。在许多实验场景中，FROC范式及相关分析工具在诊断系统性能评估方面比二元和ROC方法具有理论和实践优势，但它在实验设计、数据分析、临床相关性以及结果解释的复杂性方面也存在一些局限性。这些问题很少被讨论，而这正是本工作的重点。
