Holt P G, Fimmel P J, Roberts L M, Keast D
Med Microbiol Immunol. 1976 Dec 1;162(3-4):209-16. doi: 10.1007/BF02120999.
The reactivity of peripheral blood leukocytes to Epstein-Barr virus-associated antigen was assessed employing two in vitro tests, leukocyte adherence inhibition (LAI) and leukocyte migration inhibition (LMI). In both tests, autologous serum from some normal subjects was shown to confer strong reactivity on weak or non-responder cells. Reactivity to purified protein derivative of tuberculin (PPD) assessed in parallel was shown to be unaffected by autologous serum. Employing the LAI system, variations in the effects of autologous serum samples collected on consecutive days was shown to be dependent on the reactivity of the leukocytes themselves, rather than changes in the activity or concentration of factors present in the serum.
采用白细胞黏附抑制（LAI）和白细胞迁移抑制（LMI）这两种体外试验，评估外周血白细胞对爱泼斯坦-巴尔病毒相关抗原的反应性。在这两种试验中，一些正常受试者的自体血清被证明能赋予弱反应性或无反应性细胞强反应性。同时评估的对结核菌素纯蛋白衍生物（PPD）的反应性显示不受自体血清影响。采用LAI系统，结果表明连续几天采集的自体血清样本效果的变化取决于白细胞自身的反应性，而非血清中存在的因子的活性或浓度变化。
