Hamman Josias H
Department of Pharmaceutical Sciences, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa.
Molecules. 2008 Aug 8;13(8):1599-616. doi: 10.3390/molecules13081599.
Many of the health benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. These biological activities include promotion of wound healing, antifungal activity, hypoglycemic or antidiabetic effects antiinflammatory, anticancer, immunomodulatory and gastroprotective properties. While the known biological activities of A. vera will be briefly discussed, it is the aim of this review to further highlight recently discovered effects and applications of the leaf gel. These effects include the potential of whole leaf or inner fillet gel liquid preparations of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation. In addition, important pharmaceutical applications such as the use of the dried A. vera gel powder as an excipient in sustained release pharmaceutical dosage forms will be outlined.
许多与芦荟相关的健康益处都归因于其叶片凝胶中所含的多糖。这些生物活性包括促进伤口愈合、抗真菌活性、降血糖或抗糖尿病作用、抗炎、抗癌、免疫调节和胃保护特性。虽然将简要讨论芦荟已知的生物活性，但本综述的目的是进一步突出最近发现的叶片凝胶的作用和应用。这些作用包括芦荟全叶或内叶凝胶液体制剂增强共同给药化合物的肠道吸收和生物利用度以及增强皮肤渗透性的潜力。此外，还将概述重要的药物应用，例如使用干燥的芦荟凝胶粉作为缓释药物剂型中的辅料。
