Smitherman Todd A, Penzien Donald B, Maizels Morris
Head Pain Center, Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Curr Pain Headache Rep. 2008 Jun;12(3):224-9. doi: 10.1007/s11916-008-0039-9.
Comorbid psychopathology has been implicated as a risk factor for the chronification and progression of migraine. Although past research has focused principally on depression and migraine, recent research consistently has confirmed that a disproportionate number of migraineurs suffer from one or more comorbid anxiety disorders. Moreover, this research has implicated anxiety disorders as factors potentially associated with migraine intractability and progression; growing evidence suggests that anxiety disorders may be even more prognostically significant than depression. This article summarizes these recent developments, considers mechanisms underlying this comorbidity, discusses strategies for assessing and managing comorbid anxiety, and notes directions for future clinical and empiric work.
共病精神病理学已被认为是偏头痛慢性化和进展的一个危险因素。尽管过去的研究主要集中在抑郁症和偏头痛上，但最近的研究一致证实，相当多的偏头痛患者患有一种或多种共病焦虑症。此外，这项研究表明焦虑症是可能与偏头痛难治性和进展相关的因素；越来越多的证据表明，焦虑症在预后方面可能比抑郁症更具重要意义。本文总结了这些最新进展，探讨了这种共病的潜在机制，讨论了评估和管理共病焦虑的策略，并指出了未来临床和实证研究的方向。
