Silverman Stuart G, Israel Gary M, Herts Brian R, Richie Jerome P
Division of Abdominal Imaging and Intervention, Department of Radiology,Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115, USA.
Radiology. 2008 Oct;249(1):16-31. doi: 10.1148/radiol.2491070783.
Despite substantial advances in the imaging-based diagnosis of renal masses, the increased detection of incidental renal masses with cross-sectional imaging poses problems to the radiologist and referring physician. Most incidental renal masses can be diagnosed with confidence and either ignored or treated without further testing. However, some renal masses, particularly small ones, remain indeterminate and require a management strategy that is both medically appropriate and practical. In this article, the literature will be reviewed and an approach to the diagnosis and management of the incidental renal mass will be suggested. Management recommendations, derived from data regarding the probability of malignancy in cystic and solid renal masses, are provided for two types of patients, those in the general population and those with limited life expectancy or co-morbidity. The Bosniak classification is used to guide the management of cystic masses, with observation reserved for selected patients, and the presumption of benignity recommended for simple-appearing cystic masses smaller than 1 cm. Among solid renal masses, a more aggressive overall approach is taken. However, additional imaging, and in selected patients, percutaneous biopsy, is recommended to diagnose benign neoplasms. Although additional studies are needed to establish risks and benefits, observation of solid masses may be considered in selected patients. Minimally invasive treatments of renal cancer (including percutaneous ablation) show promise but at the same time challenge the radiologist to review the approach to the incidental renal mass.
尽管基于成像的肾肿块诊断取得了重大进展,但横断面成像技术对偶然发现的肾肿块检测增加,给放射科医生和转诊医生带来了问题。大多数偶然发现的肾肿块可以确诊,无需进一步检查即可忽略或治疗。然而,一些肾肿块,尤其是小肿块,仍然难以确定,需要一种既符合医学要求又切实可行的管理策略。本文将回顾相关文献,并提出一种偶然发现的肾肿块的诊断和管理方法。根据囊性和实性肾肿块的恶性概率数据,为两类患者提供管理建议,一类是普通人群,另一类是预期寿命有限或患有合并症的患者。采用博斯尼亚克分类法指导囊性肿块的管理,部分患者可进行观察,对于小于1cm的外观简单的囊性肿块,建议假定为良性。对于实性肾肿块,总体采取更积极的方法。然而,建议进行额外的成像检查,对于部分患者,建议进行经皮活检以诊断良性肿瘤。尽管需要更多研究来确定风险和益处,但对于部分患者可考虑对实性肿块进行观察。肾癌的微创治疗(包括经皮消融)显示出前景,但同时也对放射科医生对偶然发现的肾肿块的处理方法提出了挑战。