• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Combination of melatonin and a peroxisome proliferator-activated receptor-gamma agonist induces apoptosis in a breast cancer cell line.

作者信息

Korkmaz Ahmet, Tamura Hiroshi, Manchester Lucien C, Ogden Gary B, Tan Dun-Xian, Reiter Russel J

机构信息

Department of Cellular and Structural Biology, University of Texas Health Science Center, St. Mary's University, San Antonio, TX, USA.

出版信息

J Pineal Res. 2009 Jan;46(1):115-6. doi: 10.1111/j.1600-079X.2008.00635.x. Epub 2008 Sep 16.

DOI:10.1111/j.1600-079X.2008.00635.x
PMID:18798787
Abstract
摘要

相似文献

1
Combination of melatonin and a peroxisome proliferator-activated receptor-gamma agonist induces apoptosis in a breast cancer cell line.褪黑素与过氧化物酶体增殖物激活受体γ激动剂联合使用可诱导乳腺癌细胞系凋亡。
J Pineal Res. 2009 Jan;46(1):115-6. doi: 10.1111/j.1600-079X.2008.00635.x. Epub 2008 Sep 16.
2
Induction of G1 phase arrest and apoptosis in MDA-MB-231 breast cancer cells by troglitazone, a synthetic peroxisome proliferator-activated receptor gamma (PPARgamma) ligand.曲格列酮（一种合成的过氧化物酶体增殖物激活受体γ（PPARγ）配体）诱导MDA-MB-231乳腺癌细胞G1期阻滞和凋亡。
Cell Biol Int. 2008 Aug;32(8):906-12. doi: 10.1016/j.cellbi.2008.04.011. Epub 2008 Apr 10.
3
The PPAR-γ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-β treated pancreatic cancer cells.过氧化物酶体增殖物激活受体-γ 激动剂曲格列酮拮抗重组干扰素-β 处理的胰腺癌细胞中 STAT-3 诱导的生存途径。
Biotechnol Adv. 2012 Jan-Feb;30(1):169-84. doi: 10.1016/j.biotechadv.2011.08.001. Epub 2011 Aug 17.
4
Peroxisome proliferator-activated receptor gamma ligands induce cell cycle arrest and apoptosis in human renal carcinoma cell lines.过氧化物酶体增殖物激活受体γ配体诱导人肾癌细胞系的细胞周期停滞和凋亡。
Acta Pharmacol Sin. 2005 Jun;26(6):753-61. doi: 10.1111/j.1745-7254.2005.00753.x.
5
Downregulation of cyclooxygenase-2 expression and activation of caspase-3 are involved in peroxisome proliferator-activated receptor-gamma agonists induced apoptosis in human monocyte leukemia cells in vitro.环氧化酶-2表达下调和半胱天冬酶-3激活参与过氧化物酶体增殖物激活受体γ激动剂诱导的人单核细胞白血病细胞体外凋亡。
Ann Hematol. 2007 Mar;86(3):173-83. doi: 10.1007/s00277-006-0205-2. Epub 2006 Nov 7.
6
Activation of peroxisome proliferator-activated receptor-gamma by troglitazone (TGZ) inhibits human lung cell growth.曲格列酮（TGZ）激活过氧化物酶体增殖物激活受体γ可抑制人肺细胞生长。
J Cell Biochem. 2005 Nov 1;96(4):760-74. doi: 10.1002/jcb.20474.
7
Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo.过氧化物酶体增殖物激活受体γ的配体（曲格列酮）在体外和体内对人类前列腺癌均具有强大的抗肿瘤作用。
Cancer Res. 1998 Aug 1;58(15):3344-52.
8
Peroxisome proliferator-activated receptor-gamma antagonists exhibit potent antiproliferative effects versus many hematopoietic and epithelial cancer cell lines.过氧化物酶体增殖物激活受体γ拮抗剂对许多造血和上皮癌细胞系表现出强大的抗增殖作用。
Anticancer Drugs. 2007 Jun;18(5):525-34. doi: 10.1097/CAD.0b013e3280200414.
9
Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis.过氧化物酶体增殖物激活受体γ激动剂通过诱导凋亡抑制人肺癌细胞生长。
Biochem Biophys Res Commun. 2000 Apr 13;270(2):400-5. doi: 10.1006/bbrc.2000.2436.
10
Differential anti-proliferative actions of peroxisome proliferator-activated receptor-gamma agonists in MCF-7 breast cancer cells.过氧化物酶体增殖物激活受体γ激动剂在MCF-7乳腺癌细胞中的不同抗增殖作用。
Biochem Pharmacol. 2006 Aug 28;72(5):530-40. doi: 10.1016/j.bcp.2006.05.009. Epub 2006 Jun 27.

引用本文的文献

1
Melatonin inhibits HCC progression through regulating the alternative splicing of NEMO.褪黑素通过调节NEMO的可变剪接来抑制肝癌进展。
Front Pharmacol. 2022 Sep 26;13:1007006. doi: 10.3389/fphar.2022.1007006. eCollection 2022.
2
Chronic Piromelatine Treatment Alleviates Anxiety, Depressive Responses and Abnormal Hypothalamic-Pituitary-Adrenal Axis Activity in Prenatally Stressed Male and Female Rats.慢性匹莫林治疗可缓解产前应激雄性和雌性大鼠的焦虑、抑郁反应及异常的下丘脑-垂体-肾上腺轴活动。
Cell Mol Neurobiol. 2022 Oct;42(7):2257-2272. doi: 10.1007/s10571-021-01100-8. Epub 2021 May 18.
3
Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities.
褪黑素在癌症治疗中的应用：现有知识与未来机遇。
Molecules. 2021 Apr 25;26(9):2506. doi: 10.3390/molecules26092506.
4
Role and Therapeutic Potential of Melatonin in Various Type of Cancers.褪黑素在各类癌症中的作用及治疗潜力
Onco Targets Ther. 2021 Mar 18;14:2019-2052. doi: 10.2147/OTT.S298512. eCollection 2021.
5
Curcumin: a therapeutic strategy in cancers by inhibiting the canonical WNT/β-catenin pathway.姜黄素：通过抑制经典 WNT/β-连环蛋白通路抑制癌症的治疗策略。
J Exp Clin Cancer Res. 2019 Jul 22;38(1):323. doi: 10.1186/s13046-019-1320-y.
6
Targeting the Canonical WNT/β-Catenin Pathway in Cancer Treatment Using Non-Steroidal Anti-Inflammatory Drugs.使用非甾体类抗炎药靶向癌症治疗中的经典 WNT/β-连环蛋白通路。
Cells. 2019 Jul 15;8(7):726. doi: 10.3390/cells8070726.
7
Could long-term administration of melatonin to prepubertal children affect timing of puberty? A clinician's perspective.对青春期前儿童长期给予褪黑素会影响青春期时间吗？临床医生视角。
Nat Sci Sleep. 2019 Jan 31;11:1-10. doi: 10.2147/NSS.S181365. eCollection 2019.
8
Melatonin May Increase Anticancer Potential of Pleiotropic Drugs.褪黑素可能会增加多效药物的抗癌潜力。
Int J Mol Sci. 2018 Dec 6;19(12):3910. doi: 10.3390/ijms19123910.
9
Melatonin: An Anti-Tumor Agent in Hormone-Dependent Cancers.褪黑素：激素依赖性癌症中的一种抗肿瘤剂。
Int J Endocrinol. 2018 Oct 2;2018:3271948. doi: 10.1155/2018/3271948. eCollection 2018.
10
Urinary 6-sulfatoxymelatonin level and breast cancer risk: systematic review and meta-analysis.尿 6-硫酸褪黑素水平与乳腺癌风险：系统评价和荟萃分析。
Sci Rep. 2017 Jul 13;7(1):5353. doi: 10.1038/s41598-017-05752-9.