线性染色体末端复制模型。
A model for replication of the ends of linear chromosomes.
作者信息
Heumann J M
出版信息
Nucleic Acids Res. 1976 Nov;3(11):3167-71. doi: 10.1093/nar/3.11.3167.
Abstract
Linear chromosomes possessing internal repeats of their terminal sequences can form intramolecular crossed-strand exchanges that allow replication of the chromosome ends. Evidence is discussed that such a mechanism may be utilized during replication of herpes simplex virus DNA and during replication of macronuclear DNA from the hypotrichous ciliate Oxytricha.
摘要
拥有末端序列内部重复的线性染色体可以形成分子内交叉链交换，从而实现染色体末端的复制。文中讨论了相关证据，表明这种机制可能在单纯疱疹病毒DNA复制过程以及来自低等多毛纲纤毛虫绿草履虫的大核DNA复制过程中被利用。
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Inverted repetitious sequences in the macronuclear DNA of hypotrichous ciliates.腹毛目纤毛虫大核DNA中的反向重复序列。
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