基因组医学的未来发展方向：发展中世界面临的挑战与机遇

The next steps for genomic medicine: challenges and opportunities for the developing world.

作者信息

Hardy Billie-Jo, Séguin Béatrice, Goodsaid Federico, Jimenez-Sanchez Gerardo, Singer Peter A, Daar Abdallah S

机构信息

McLaughlin-Rotman Centre for Global Health, Program on Life Sciences, Ethics and Policy, University Health Network and University of Toronto, MaRS Centre, South Tower, Suite 406, 101 College Street, Toronto, Ontario M5G 1L7, Canada.

出版信息

Nat Rev Genet. 2008 Oct;9 Suppl 1:S23-7. doi: 10.1038/nrg2444.

DOI:10.1038/nrg2444

PMID:18802418

Abstract

This is a historical moment on the path to genomic medicine - the point at which theory is about to be translated into practice. We have previously described human genome variation studies taking place in Mexico, India, Thailand, and South Africa. Such investments into science and technology will enable these countries to embark on the path to the medical and health applications of genomics, and to benefit economically. Here we provide a perspective on the challenges and opportunities facing these and other countries in the developing world as they begin to harness genomics for the benefit of their populations.

摘要

这是基因组医学道路上的一个历史性时刻——理论即将转化为实践的时刻。我们之前描述过在墨西哥、印度、泰国和南非开展的人类基因组变异研究。对科学技术的此类投资将使这些国家走上基因组学在医疗和健康领域应用的道路，并获得经济利益。在此，我们阐述了发展中世界的这些国家和其他国家在开始利用基因组学造福本国人民时所面临的挑战和机遇。