Steinwender Clemens, Hönig Simon, Leisch Franz, Hofmann Robert
Cardiovascular Division, City Hospital Linz, Linz, Austria.
J Cardiovasc Electrophysiol. 2009 Feb;20(2):147-52. doi: 10.1111/j.1540-8167.2008.01299.x. Epub 2008 Sep 17.
Catheter-based pulmonary vein isolation (PVI) is an established therapy to treat patients with paroxysmal atrial fibrillation. We evaluated the efficacy of a simplified interventional procedure for PVI by using a single mesh catheter for mapping as well as ablation and with guidance of fluoroscopic imaging only.
Forty-eight patients with paroxysmal atrial fibrillation were screened by cardiac computed tomography for their anatomical suitability to undergo PVI with the high-density mesh ablator catheter as the only left atrial device. The procedure was performed in 26 patients (12 males, mean age 61 years) who met the criteria of four clearly separated pulmonary veins (PVs) with an ostial diameter of 15-25 mm. No three-dimensional mapping systems or additional ablation devices were used. In all 26 patients, all four PVs could be accessed and mapped with the high-density mesh ablator catheter. Electrical isolation was achieved in 99 of 102 (97%) of the pulmonary veins that revealed PV potentials. Mean total procedure time and fluoroscopy time were 187 +/- 36 minutes and 34.6 +/- 10.0 minutes, respectively.
The single-catheter approach using the high-density mesh ablator catheter for mapping as well as ablation reveals a high acute success rate of PVI while, at the same time, reducing the complexity of the procedure, and the procedure time. Long-term data on clinical success are needed to justify this simplified approach.
基于导管的肺静脉隔离术(PVI)是治疗阵发性心房颤动患者的一种成熟疗法。我们评估了一种简化的介入性PVI手术的疗效,该手术使用单一网状导管进行标测和消融,仅在荧光透视成像引导下进行。
通过心脏计算机断层扫描筛选出48例阵发性心房颤动患者,以确定他们是否适合使用高密度网状消融导管作为唯一的左心房装置进行PVI。该手术在26例患者(12例男性,平均年龄61岁)中进行,这些患者符合四个明显分开的肺静脉(PVs)的标准,肺静脉口直径为15 - 25毫米。未使用三维标测系统或其他消融装置。在所有26例患者中,均可用高密度网状消融导管进入并标测所有四条肺静脉。在显示肺静脉电位的102条肺静脉中的99条(97%)实现了电隔离。平均总手术时间和透视时间分别为187±36分钟和34.6±10.0分钟。
使用高密度网状消融导管进行标测和消融的单导管方法显示PVI的急性成功率很高,同时降低了手术的复杂性和手术时间。需要长期的临床成功数据来证明这种简化方法的合理性。