Briggs Farran, Usrey W Martin
Department of Neurobiology, Physiology & Behavior, Center for Neuroscience, University of California, Davis, CA, United States.
Curr Opin Neurobiol. 2008 Aug;18(4):403-7. doi: 10.1016/j.conb.2008.09.002. Epub 2008 Oct 6.
Although it is now generally accepted that the thalamus is more than a simple relay of sensory signals to the cortex, we are just beginning to gain an understanding of how corticothalamic feedback influences sensory processing. Results from an increasing number of studies across sensory systems and different species reveal effects of feedback both on the receptive fields of thalamic neurons and on the transmission of sensory information between the thalamus and cortex. Importantly, these studies demonstrate that the cortico-thalamic projection cannot be viewed in isolation, but must be considered as an integral part of a thalamo-corticothalamic circuit which intimately interconnects the thalamus and cortex for sensory processing.
尽管现在人们普遍认为丘脑不仅仅是感觉信号向皮层的简单中继站，但我们才刚刚开始了解皮质丘脑反馈如何影响感觉处理。来自越来越多跨感觉系统和不同物种的研究结果揭示了反馈对丘脑神经元感受野以及丘脑与皮层之间感觉信息传递的影响。重要的是，这些研究表明，皮质丘脑投射不能孤立地看待，而必须被视为丘脑-皮质-丘脑回路的一个组成部分，该回路将丘脑和皮层紧密连接起来以进行感觉处理。
