Roper S N, Mena I, King W A, Schweitzer J, Garrett K, Mehringer C M, McBride D
Divisions of Neurosurgery, UCLA-Harbor Medical Center.
J Nucl Med. 1991 Sep;32(9):1684-7.
Technetium-99m-hexamethylpropyleneamine (HMPAO) SPECT and x-ray CT were compared in 15 patients with acute closed-head injury. There were 44 focal lesions in all. Fifteen (34%) lesions were seen on both x-ray and SPECT. Seventeen (39%) lesions were seen only on SPECT. Twelve (27%) of the lesions were seen on x-ray tomography only. Of the lesions seen on x-ray tomography but not on SPECT, two were subarachnoid hemorrhage, two were thin subdural hematomas, and eight were contusions. This study shows that SPECT can detect focal disturbances of cerebral blood flow that are not seen on x-ray tomography. It also suggests that there are two types of contusions: those with a decreased cerebral blood flow (i.e., detectable on SPECT) and those with a cerebral blood flow equal to that of the surrounding brain.
对15例急性闭合性颅脑损伤患者的锝-99m-六甲基丙烯胺肟（HMPAO）单光子发射计算机断层扫描（SPECT）和X线计算机断层扫描（CT）进行了比较。总共发现44个局灶性病变。15个（34%）病变在X线和SPECT上均可见。17个（39%）病变仅在SPECT上可见。12个（27%）病变仅在X线断层扫描上可见。在X线断层扫描上可见但在SPECT上未见的病变中，2个为蛛网膜下腔出血，2个为薄层硬膜下血肿，8个为挫伤。本研究表明，SPECT能够检测出X线断层扫描上未见的脑血流局灶性紊乱。这也提示存在两种类型的挫伤：脑血流减少的挫伤（即在SPECT上可检测到）和脑血流与周围脑组织相等的挫伤。
