Musty R E, Lindsey C J, Carlini E A
Psychopharmacology (Berl). 1976 Jul 28;48(2):175-9. doi: 10.1007/BF00423257.
6-Hydroxydopamine (6OH-DA) pretreatment increased the aggressive behavior induced by marihuana in REM sleep-deprived rats. Brain catecholamine assays revealed that 6OH-DA depleted popamine (DA) and norepinephrine (NE) to a different extent, increasing the DA/NE ratio. Intraventricular injection of NE significantly decreased the aggressive behavior of these animals, whereas control solution or DA injections had no effect. The possible role played by DA and NE in the aggressive behavior induced by marihuana in REM sleep-deprived rats is discussed.
6-羟基多巴胺（6OH-DA）预处理增强了快速眼动睡眠剥夺大鼠中由大麻引起的攻击行为。脑儿茶酚胺测定显示，6OH-DA不同程度地消耗了多巴胺（DA）和去甲肾上腺素（NE），提高了DA/NE比值。脑室内注射NE显著降低了这些动物的攻击行为，而注射对照溶液或DA则没有效果。本文讨论了DA和NE在快速眼动睡眠剥夺大鼠中由大麻引起的攻击行为中可能发挥的作用。
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