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睡眠:剥夺“异相”期后大鼠对电惊厥休克阈值的变化

Sleep: changes in threshold to electroconvulsive shock in rats after deprivation of "paradoxical" phase.

作者信息

Cohen H B, Dement W C

出版信息

Science. 1965 Dec 3;150(3701):1318-9. doi: 10.1126/science.150.3701.1318.

Abstract

Rats were deprived of paradoxical (radid eye movement or REM) sleep for a 6-day period but were allowed substantial non-REM (slow wave) sleep. Thresholds for electroconvulsive shock dropped significantly after deprivation in all these animals, but thresholds in control animals treated in a similar manner, but allowed REM sleep exhibited no change. Deprivation seems to heighten neural excitability.

摘要

大鼠被剥夺异相睡眠(快速眼动睡眠或REM睡眠)达6天,但允许有充足的非快速眼动睡眠(慢波睡眠)。在所有这些动物中,剥夺睡眠后电惊厥休克阈值显著下降,但以类似方式处理但允许REM睡眠的对照动物的阈值没有变化。睡眠剥夺似乎会增强神经兴奋性。

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