Irita Kazuo, Yoshimura Hayashi, Sakaguchi Yoshiro, Takamatsu Chihiro, Tokuda Kentaro
Department of Anesthesiology and Critical Care Medicine, Kyushu University Hospital, Fukuoka 812-8582.
Masui. 2008 Sep;57(9):1109-16.
According to a survey of anesthesia-related critical incidents by the Japanese Society of Anesthesiologists, hemorrhage was the major cause of cardiac arrest developing in the operating room. To deal with critical hemorrhage swiftly, not only cooperation between anesthesiologists and surgeons but also the linkage of operating rooms with transfusion management divisions and the blood center is important. It is desirable for the hospital transfusion committee to prepare hospital regulations on 'actions to be taken to manage critical hemorrhage', and practice the implementation of these guidelines by simulated drills. When critical hemorrhage occurs, a person in charge is appointed, and an emergency is declared (call for manpower and notification of the emergency to the transfusion management divisions). A person in charge comprehensively assesses the hemostatic condition, hemodynamics, laboratory data, and blood product supply system, and consults the operator regarding the continuation of surgery or changing surgical procedures. When time is short, the cross-matching test is omitted, and the ABO-identical blood is used. When a supply of the identical ABO-type blood is not available, compatible blood type is used. The evolving concept of hemostatic resuscitation seems to be important to prevent coagulopathy, which easily develops during massive hemorrhage. Anesthesiologists should be aware of the risk of such an emergency transfusion and procedures to be taken to switch to transfusion of the ABO-identical blood. Establishment of a hospital emergency transfusion system depends on the overall capability of the critical and crisis management systems of the hospital.
根据日本麻醉医师协会对麻醉相关危急事件的一项调查,出血是手术室中心脏骤停的主要原因。为了迅速应对严重出血情况,麻醉医师与外科医生之间的合作以及手术室与输血管理部门和血库之间的联动都很重要。医院输血委员会最好制定关于“严重出血管理应采取的行动”的医院规定,并通过模拟演练来实践这些指南的实施。当发生严重出血时,指定负责人并宣布紧急情况(召集人力并通知输血管理部门紧急情况)。负责人全面评估止血情况、血流动力学、实验室数据和血液制品供应系统,并就手术的继续进行或改变手术程序与手术人员进行协商。时间紧迫时,省略交叉配血试验,使用ABO血型相同的血液。当没有相同ABO血型的血液供应时,使用相容血型的血液。止血复苏这一不断发展的概念对于预防在大量出血期间容易发生的凝血病似乎很重要。麻醉医师应意识到这种紧急输血的风险以及切换到输注ABO血型相同血液时应采取的程序。医院紧急输血系统的建立取决于医院危急和危机管理系统的整体能力。