Phibbs C S, Bateman D A, Schwartz R M
Division of Health Policy and Management, Columbia University School of Public Health, New York, NY.
JAMA. 1991 Sep 18;266(11):1521-6.
--To examine the added neonatal cost and length of hospital stay associated with fetal cocaine exposure.
--All cocaine-exposed infants in the study population (n = 355) were compared with a random sample of unexposed infants (n = 199). Regression analysis was used to control for the independent effects of maternal age, smoking, alcohol consumption, prenatal care, race, gravidity, and sex of the infant.
--A large, public, inner-city hospital studied from 1985 to 1986.
--All infants were routinely tested for illicit substances, records were reviewed for maternal histories of substance abuse, and all known cocaine-exposed singleton infants were included.
--Cost and length of stay until each infant was medically cleared for hospital discharge and cost and length of stay until each infant was actually discharged from the hospital.
--Neonatal hospital costs until medically cleared for discharge were $5200 more for cocaine-exposed infants than for unexposed infants (a difference of $7957 vs $2757 [P = .003]). The costs of infants remaining in the nursery while awaiting home and social evaluation or foster care placement increased this difference by more than $3500 (P less than .0001). Compared with other forms of cocaine, fetal exposure to crack was associated with much larger cost increases ($6735 vs $1226). Exposure to other illicit substances in addition to cocaine was also associated with much larger cost increases ($8450 vs $1283).
--At the national level, we estimate that these individual medical costs add up to about $500 million. The large magnitude of these costs indicates that effective treatment programs for maternal cocaine abusers could yield savings within their first year of operation.
研究与胎儿可卡因暴露相关的新生儿额外费用及住院时间。
将研究人群中所有可卡因暴露婴儿(n = 355)与未暴露婴儿的随机样本(n = 199)进行比较。采用回归分析来控制母亲年龄、吸烟、饮酒、产前护理、种族、妊娠次数及婴儿性别的独立影响。
1985年至1986年对一家大型市内公立医院进行研究。
所有婴儿均接受非法物质常规检测,查阅母亲药物滥用史记录,纳入所有已知的可卡因暴露单胎婴儿。
每位婴儿医学上获准出院前的费用及住院时间,以及每位婴儿实际出院前的费用及住院时间。
在医学上获准出院前,可卡因暴露婴儿的新生儿住院费用比未暴露婴儿多5200美元(分别为7957美元和2757美元,P = 0.003)。婴儿在等待家庭和社会评估或寄养安置期间留在保育室的费用使这一差异增加了3500多美元(P < 0.0001)。与其他形式的可卡因相比,胎儿接触快克可卡因导致的费用增加幅度更大(6735美元对1226美元)。除可卡因外接触其他非法物质也导致费用增加幅度更大(8450美元对1283美元)。
在国家层面上,我们估计这些个体医疗费用总计约5亿美元。这些费用数额巨大,表明针对母亲可卡因滥用者的有效治疗方案在运行的第一年即可节省开支。