Tandon Yasmeen K, Yang Marjorie F, Baron Elma D
North Eastern Ohio Universities Colleges of Medicine, Rootstown, OH, USA.
Photodermatol Photoimmunol Photomed. 2008 Oct;24(5):222-30. doi: 10.1111/j.1600-0781.2008.00376.x.
Photodynamic therapy (PDT) is a light treatment modality which involves either systemic or local application of a photosensitizing compound, which preferentially deposits in the target cells, and is then followed by selective illumination of the lesion with visible light. The purpose of this study was to review the literature to examine the success, side effects, and different protocols used thus far to treat psoriasis using PDT.
A thorough review of the literature was performed and analyzed.
After a thorough review of the literature, PDT remains a potential treatment for psoriasis. Clinical improvement has been observed in most studies. The major limiting factor seen in many of the studies was the side effect of pain and burning sensations associated with PDT. This highlights the need for other photosensitizers with better tolerability profiles.
光动力疗法（PDT）是一种光治疗方式，涉及全身或局部应用一种光敏化合物，该化合物优先沉积在靶细胞中，随后用可见光对病变部位进行选择性照射。本研究的目的是回顾文献，以考察迄今为止使用光动力疗法治疗银屑病的成功率、副作用及不同方案。
对文献进行了全面回顾与分析。
在对文献进行全面回顾后，光动力疗法仍是银屑病的一种潜在治疗方法。大多数研究中均观察到临床改善。许多研究中所见的主要限制因素是与光动力疗法相关的疼痛和烧灼感副作用。这凸显了对具有更好耐受性的其他光敏剂的需求。
