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一名患有T细胞淋巴瘤和念珠菌败血症的HIV阳性儿童体内白细胞介素-10水平过高。

Hyper interleukin-10 in an HIV-positive child with t-cell lymphoma and candidal sepsis.

作者信息

Lighter Jennifer, Tse Doris B, Kaul Aditya, Borkowsky William

机构信息

Saul Krugman Division of Pediatric Infectious Diseases and Immunology, New York University School of Medicine, New York, New York.

出版信息

J Int Assoc Physicians AIDS Care (Chic). 2008 Sep-Oct;7(5):228-31. doi: 10.1177/1545109708325467. Epub 2008 Sep 23.

Abstract

We describe a case in which a human immunodeficiency virus (HIV)-positive child presented in severe metabolic acidosis secondary to his candidal sepsis and T-cell lymphoma, a rare finding in pediatric AIDS. Significantly elevated levels of Interleukin-10 (IL-10) were found in the patient's serum, which may have played a role in acute demise.

摘要

我们描述了一例病例,一名感染人类免疫缺陷病毒(HIV)的儿童因念珠菌败血症和T细胞淋巴瘤出现严重代谢性酸中毒,这在儿童艾滋病中是罕见的发现。在患者血清中发现白细胞介素-10(IL-10)水平显著升高,这可能在其急性死亡中起了作用。

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