Zhang Alan L, Exner G Ulrich, Wenger Dennis R
Department of Orthopaedic Surgery, University of California-San Diego, San Diego, CA, USA.
J Pediatr Orthop. 2008 Oct-Nov;28(7):752-6. doi: 10.1097/BPO.0b013e3181875b46.
Progressive genu varum with disturbance of medial tibial physeal growth (classic Blount disease) is a well-studied phenomenon, and in rare cases, genu varum can occur because of medial distal femoral physeal growth disturbance (so-called femoral Blount disease). To our knowledge, progressive genu valgum caused by disturbance of lateral distal femoral physeal growth has not been described.
This article presents the history, clinical findings, imaging studies, results of surgical treatment, and speculation regarding the etiology of this disorder in 2 girls.
Both patients were overweight girls without a history of injury or prior medical disorder who presented with relatively rapid progression of knock-kneed deformity. Magnetic resonance imaging studies demonstrated unusual circular peglike disturbances of the lateral distal femoral physes. Treatments in both cases included corrective distal femoral osteotomy and epiphysiodesis to prevent further deformity.
Obesity and repetitive microtrauma, superimposed on genetic factors (physis that is sensitive to compressive forces), may contribute to the etiology of this rare disorder.
伴有胫骨内侧骨骺生长紊乱的进行性膝内翻(典型的布朗特病)是一种已得到充分研究的现象,在罕见情况下,膝内翻可因股骨远端内侧骨骺生长紊乱而发生(所谓的股骨布朗特病)。据我们所知,由股骨远端外侧骨骺生长紊乱引起的进行性膝外翻尚未见报道。
本文介绍了2名女孩的病史、临床检查结果、影像学研究、手术治疗结果以及对该疾病病因的推测。
两名患者均为超重女孩,无受伤史或既往病史,均表现为膝外翻畸形进展相对较快。磁共振成像研究显示股骨远端外侧骨骺有异常的圆形钉状紊乱。两例患者的治疗均包括股骨远端截骨矫正术和骨骺阻滞术以防止进一步畸形。
肥胖和反复微小创伤,叠加遗传因素(对压力敏感的骨骺),可能是这种罕见疾病病因的一部分。