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肥胖与肺部:3. 肥胖、呼吸与重症监护。

Obesity and the lung: 3. Obesity, respiration and intensive care.

作者信息

Malhotra A, Hillman D

机构信息

Pulmonary and Critical Care and Sleep Medicine Divisions, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

出版信息

Thorax. 2008 Oct;63(10):925-31. doi: 10.1136/thx.2007.086835.

Abstract

Obesity is a major problem from a public health perspective and a difficult practical matter for intensivists. The obesity pandemic has required treating clinicians to develop an appreciation of the substantial pathophysiological effects of obesity on the various organ systems. The important physiological concepts are illustrated by focusing on obstructive sleep apnoea, obesity hypoventilation syndrome, abdominal compartment syndrome and ventilatory management of the obese patient with acute respiratory distress syndrome.

摘要

从公共卫生角度来看,肥胖是一个重大问题,对于重症监护医生而言也是一个棘手的实际问题。肥胖症的流行要求临床治疗医生认识到肥胖对各个器官系统产生的重大病理生理影响。通过关注阻塞性睡眠呼吸暂停、肥胖低通气综合征、腹腔间隔室综合征以及急性呼吸窘迫综合征肥胖患者的通气管理来说明这些重要的生理概念。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1940/2711075/ebd5706ac7f0/nihms-88985-f0001.jpg

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本文引用的文献

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Effect of intra-abdominal pressure on respiratory mechanics.腹腔内压力对呼吸力学的影响。
Acta Clin Belg. 2007;62 Suppl 1:78-88. doi: 10.1179/acb.2007.62.s1.011.
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Pathophysiology of adult obstructive sleep apnea.成人阻塞性睡眠呼吸暂停的病理生理学
Proc Am Thorac Soc. 2008 Feb 15;5(2):144-53. doi: 10.1513/pats.200707-114MG.
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Cytokine release following recruitment maneuvers.募集策略后的细胞因子释放。
Chest. 2007 Nov;132(5):1434-9. doi: 10.1378/chest.07-1551. Epub 2007 Oct 9.
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The impact of obesity on outcome after major colorectal surgery.肥胖对大肠大手术后结局的影响。
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