Malhotra A, Hillman D
Pulmonary and Critical Care and Sleep Medicine Divisions, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Thorax. 2008 Oct;63(10):925-31. doi: 10.1136/thx.2007.086835.
Obesity is a major problem from a public health perspective and a difficult practical matter for intensivists. The obesity pandemic has required treating clinicians to develop an appreciation of the substantial pathophysiological effects of obesity on the various organ systems. The important physiological concepts are illustrated by focusing on obstructive sleep apnoea, obesity hypoventilation syndrome, abdominal compartment syndrome and ventilatory management of the obese patient with acute respiratory distress syndrome.
从公共卫生角度来看,肥胖是一个重大问题,对于重症监护医生而言也是一个棘手的实际问题。肥胖症的流行要求临床治疗医生认识到肥胖对各个器官系统产生的重大病理生理影响。通过关注阻塞性睡眠呼吸暂停、肥胖低通气综合征、腹腔间隔室综合征以及急性呼吸窘迫综合征肥胖患者的通气管理来说明这些重要的生理概念。