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土耳其一家三级护理新生儿病房中早产儿视网膜病变的筛查:发生率、结局及危险因素分析。

Screening for retinopathy of prematurity in a tertiary care newborn unit in Turkey: frequency, outcomes, and risk factor analysis.

作者信息

Mutlu Fatih Mehmet, Altinsoy H Ibrahim, Mumcuoglu Tarkan, Kerimoglu Hürkan, Kiliç Selim, Kul Mustafa, Sarici S Umit, Alpay Faruk

机构信息

Department of Ophthalmology, Gulhane Military Medical Academy and Medical School, Ankara, Turkey.

出版信息

J Pediatr Ophthalmol Strabismus. 2008 Sep-Oct;45(5):291-8. doi: 10.3928/01913913-20080901-12.

DOI:10.3928/01913913-20080901-12
PMID:18825902
Abstract

PURPOSE

To report the frequency, risk factors, and outcomes of screening for retinopathy of prematurity (ROP).

METHODS

Data of neonates with a gestational age of 34 weeks or less were analyzed and the predictors on the development of ROP were determined by using logistic regression analysis.

RESULTS

Of the 318 neonates, the frequency of ROP was 37.1% for any stage and 7.2% for stage 3 or greater. Treatment was needed in 16.1% of neonates with ROP. No treatment was required in neonates with a gestational age of greater than 32 weeks. Oxygen therapy, sepsis, gestational age of 32 weeks or less, and birth weight of less than 1,250 g were determined as the independent risk factors.

CONCLUSIONS

Although frequency of ROP in Turkey is similar to that in the United States, the rate of severe ROP necessitating treatment seems to be higher in Turkey. Neonates with a gestational age of 32 weeks or less, a birth weight of less than 1,250 g, sepsis, and oxygen therapy may have a greater risk of developing ROP and screening should be intensified in the presence of these risk factors.

摘要

目的

报告早产儿视网膜病变(ROP)筛查的频率、危险因素及结果。

方法

分析孕周34周及以下新生儿的数据,采用逻辑回归分析确定ROP发生的预测因素。

结果

在318例新生儿中,任何阶段ROP的发生率为37.1%,3期及以上为7.2%。16.1%的ROP新生儿需要治疗。孕周大于32周的新生儿无需治疗。氧疗、败血症、孕周32周及以下和出生体重小于1250g被确定为独立危险因素。

结论

尽管土耳其ROP的发生率与美国相似,但在土耳其需要治疗的严重ROP发生率似乎更高。孕周32周及以下、出生体重小于1250g、败血症和氧疗的新生儿发生ROP的风险可能更高,存在这些危险因素时应加强筛查。

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