Rasoulinejad Seyed Ahmad, Montazeri Mohammad
Department of Ophthalmology, Babol University of Medical Sciences, Babol, Iran.
Young Researchers Club, Islamic Azad University, Babol branch, Babol, Iran.
Open Ophthalmol J. 2016 Feb 29;10:17-21. doi: 10.2174/1874364101610010017. eCollection 2016.
An important cause of avoidable childhood blindness is retinopathy of prematurity (ROP) in countries with high human development index and also in some emerging economies countries. To date, no research have been conducted on analyzing data of ROP prevalence in Babol, and this is the first research performed on ROP in this area.
All VLBW babies who referred to Babol ophthalmology center over the seven years, from February 2007 to December 2013 were enrolled in this descriptive cross-sectional research. A team of researchers recorded patients' information completely in check lists. A single experienced ophthalmologist performed ophthalmologic examination of patients.
The incidence of ROP of any stage in Babol was determined to be 306 (45%) of all babies enrolled in this study. In present study, key risk factors of ROP were low gestational age, oxygen therapy more than five days and low birth weight.
The findings of current study demonstrate that the main risk factors of developing ROP in newborns are multiple gestation, low birth weight, oxygen therapy for more than five day. Therefore, the progression of ROP to blindness will be prevented by a high index of suspicion, suitable screening, prompt diagnosis, and early treatment.
在人类发展指数较高的国家以及一些新兴经济体国家，可避免的儿童失明的一个重要原因是早产儿视网膜病变（ROP）。迄今为止，尚未对巴博勒地区ROP患病率的数据进行分析，这是该地区首次针对ROP开展的研究。
在2007年2月至2013年12月的七年时间里，所有转诊至巴博勒眼科中心的极低出生体重儿均纳入了这项描述性横断面研究。一组研究人员在检查表中完整记录了患者信息。由一名经验丰富的眼科医生对患者进行眼科检查。
巴博勒地区所有纳入本研究的婴儿中，任何阶段ROP的发生率为306例（45%）。在本研究中，ROP的关键危险因素为孕周小、吸氧超过五天和低出生体重。
当前研究结果表明，新生儿发生ROP的主要危险因素是多胎妊娠、低出生体重、吸氧超过五天。因此，通过高度的怀疑指数、适当的筛查、及时的诊断和早期治疗，可以预防ROP发展为失明。
