强迫症患者内侧额叶脑血流升高：一项单光子发射计算机断层扫描研究
Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: a SPECT study.
作者信息
Machlin S R, Harris G J, Pearlson G D, Hoehn-Saric R, Jeffery P, Camargo E E
机构信息
Department of Psychiatry and Behavioral Sciences, Johns Hopkins Medical Institutions, Baltimore, MD.
出版信息
Am J Psychiatry. 1991 Sep;148(9):1240-2. doi: 10.1176/ajp.148.9.1240.
PMID:1883006
Abstract
Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.
摘要
采用单光子发射计算机断层扫描技术对10名强迫症患者和8名对照受试者进行了局部脑血流量测量。患者内侧额叶与整个皮层血流量的比值显著更高；这与症状严重程度无关，但与焦虑呈负相关。未发现眶额叶血流量有差异。
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