Patil Nilesh, Lee Kevin, Goodman Stuart B
Department of Orthopaedic Surgery, Stanford University Medical Center, Stanford, California, USA.
J Biomed Mater Res B Appl Biomater. 2009 Apr;89(1):242-51. doi: 10.1002/jbm.b.31198.
Conventional porous-coated joint prostheses used in hip and knee reconstruction have demonstrated good clinical results, however, these implants possess some inherent shortcomings such as low volumetric porosity, suboptimal frictional characteristics, and higher modulus of elasticity relative to that of bone. Porous tantalum, a novel porous biomaterial was developed to address these limitations. Extensive laboratory studies have revealed that porous tantalum has physical, mechanical and tissue in growth properties that makes it a potentially improved biomaterial particularly in complex joint reconstructions. Porous tantalum is a highly porous biomaterial with good biocompatibility, excellent corrosion resistance, and high coefficient of friction. The short term clinical results of porous tantalum in primary hip, revision hip, and knee reconstructive surgery are encouraging but further studies will be needed to determine whether the theoretical advantages of porous tantalum can provide long term biological fixation and stability. This review presents the biomaterial properties and clinical results of porous tantalum devices in hip and knee reconstructive surgeries.
用于髋关节和膝关节重建的传统多孔涂层关节假体已显示出良好的临床效果，然而，这些植入物存在一些固有缺点，如体积孔隙率低、摩擦特性不理想以及相对于骨的弹性模量较高。钽多孔体，一种新型多孔生物材料，被开发出来以解决这些局限性。广泛的实验室研究表明，钽多孔体具有物理、机械和组织生长特性，这使其成为一种潜在的改良生物材料，特别是在复杂关节重建中。钽多孔体是一种具有良好生物相容性、优异耐腐蚀性和高摩擦系数的高度多孔生物材料。钽多孔体在初次髋关节、翻修髋关节和膝关节重建手术中的短期临床结果令人鼓舞，但需要进一步研究以确定钽多孔体的理论优势能否提供长期生物固定和稳定性。本综述介绍了钽多孔体装置在髋关节和膝关节重建手术中的生物材料特性和临床结果。
