通过微接触“点击”化学制备的碳水化合物微阵列。
Carbohydrate microarrays by microcontact "click" chemistry.
作者信息
Michel Olaf, Ravoo Bart Jan
机构信息
Organic Chemistry Institute, Center for Nanotechnology, Westfälische Wilhelms-Universität Münster, Münster, Germany.
出版信息
Langmuir. 2008 Nov 4;24(21):12116-8. doi: 10.1021/la802304w. Epub 2008 Oct 7.
PMID:18837529
Abstract
Carbohydrate microarrays can be prepared by microcontact printing of carbohydrate alkyne conjugates on azide self-assembled monolayers (SAMs). The carbohydrates are immobilized by a "click" reaction in the contact area between the stamp and the substrate. The immobilized carbohydrates retain their characteristic selectivity toward lectins.
摘要
碳水化合物微阵列可通过将碳水化合物炔烃共轭物微接触印刷在叠氮化物自组装单分子层（SAMs）上来制备。碳水化合物在印章与底物之间的接触区域通过“点击”反应固定。固定的碳水化合物对凝集素保持其特征选择性。
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