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孕期复发性菊池-藤本病:1例演变为系统性红斑狼疮的病例报告及已发表文献综述

Recurrent Kikuchi-Fujimoto disease during pregnancy: report of case evolving into systemic lupus erythematosus and review of published work.

作者信息

Alijotas-Reig Jaume, Casellas-Caro Manel, Ferrer-Oliveras Raquel, Cabero-Roura Lluis, Vilardell-Tarres Miquel

机构信息

Systemic Autoimmune Disease Unit, Service of Internal Medicine I, University Hospital of Vall d'Hebron, Barcelona, Spain.

出版信息

J Obstet Gynaecol Res. 2008 Aug;34(4 Pt 2):595-8. doi: 10.1111/j.1447-0756.2008.00727.x.

Abstract

Kikuchi-Fujimoto disease (KFD) is a distinctive, benign type of necrotizing lymphadenitis. KFD is a rare entity, especially during pregnancy. Although first described in Japan, subsequently it has been reported in the West. We communicate herein a case of KFD in African women with bouts during pregnancy. Diagnosis was difficult because peripheral enlarged lymph nodes were absent and an extended differential diagnosis and adequate work-up was necessary. The patient suffered a miscarriage coinciding with a KFD bout. Further pregnancies were uneventful. Follow up showed that KFD evolved into a systemic lupus erythematosus-like syndrome.

摘要

菊池-藤本病(KFD)是一种独特的良性坏死性淋巴结炎。KFD是一种罕见疾病,在孕期尤为少见。尽管最初在日本被描述,但随后在西方也有报道。我们在此报告一例非洲女性孕期患KFD且病情发作的病例。诊断困难,因为外周无肿大淋巴结,需要进行广泛的鉴别诊断和充分检查。患者在KFD发作时发生流产。后续妊娠过程顺利。随访显示KFD演变成了类似系统性红斑狼疮的综合征。

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