Gionanlis Lazaros, Katsounaros Marios, Bamihas Gerasimos, Fragidis Stelios, Veneti Panagiota, Sombolos Kostas
Department of Nephrology, General Hospital G. Papanikolaou, Thessaloniki, Greece.
Ren Fail. 2009;31(2):144-8. doi: 10.1080/08860220802595518.
Kikuchi-Fujimoto disease (KFD) is a benign and self-limited disease of unknown etiology that affects mainly young women. It presents with localized lymphadenopathy, usually cervical, accompanied with fever, night sweats, and leucopenia. KFD has been rarely described in association with autoimmune disorders, mainly systemic lupus erythematosus (SLE). We report the case of a young patient presenting with KFD coinciding with SLE. The association of KFD and SLE is reviewed. Moreover, a possible pathogenetic role of Ebstein-Barr virus linking the two clinical entities is discussed.
菊池-藤本病（KFD）是一种病因不明的良性自限性疾病，主要影响年轻女性。它表现为局限性淋巴结病，通常为颈部淋巴结病，并伴有发热、盗汗和白细胞减少。KFD很少与自身免疫性疾病相关，主要是系统性红斑狼疮（SLE）。我们报告了一例同时患有KFD和SLE的年轻患者。对KFD和SLE的关联进行了综述。此外，还讨论了爱泼斯坦-巴尔病毒将这两种临床实体联系起来的可能致病作用。
