Grandguillot L, Fairbrother J M, Vrins A
Departement de pathologie et de microbiologie, Faculté de Médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec.
Can J Vet Res. 1991 Jan;55(1):50-5.
A protected catheter brush introduced by fiberoptic bronchoscopy was used to sample the tracheai and bronchial mucosa in 28 horses with small airway disease. Tracheal and bronchial brushings were examined for the presence of fungi, aerobic and anaerobic bacteria, and a cytoiogical evaluation was also done on fluid collected by the bronchoalveolar lavage (BAL) technique. Microorganisms (bacteria and fungi) were isolated more often in tracheal brushings (53.6%) than in bronchial brushings (10.7%). Anaerobic bacteria were not isolated. Results of this study indicate that fiberoptic bronchoscopy using a protected catheter brush is an easy and practical technique to obtain minimally contaminated samples for isolation of microorganisms from the lower respiratory tract of horses. However, no association was observed between isolation of high numbers of microorganisms from the bronchi and severity of small airway disease.
使用经纤维支气管镜插入的保护性导管刷对28匹患有小气道疾病的马的气管和支气管黏膜进行采样。对气管和支气管刷检样本进行真菌、需氧菌和厌氧菌检测，并对通过支气管肺泡灌洗（BAL）技术收集的液体进行细胞病理学评估。气管刷检样本中分离出微生物（细菌和真菌）的频率（53.6%）高于支气管刷检样本（10.7%）。未分离出厌氧菌。本研究结果表明，使用保护性导管刷的纤维支气管镜检查是一种简便实用的技术，可获取污染最小的样本，用于从马的下呼吸道分离微生物。然而，未观察到支气管中大量微生物的分离与小气道疾病严重程度之间存在关联。
