Masuda Tatsuru, Fujita Yuichi
Department of General Systems Studies, Graduate School of Arts and Sciences, The University of Tokyo, Komaba 3-8-1, Tokyo, 153-8902, Japan.
Photochem Photobiol Sci. 2008 Oct;7(10):1131-49. doi: 10.1039/b807210h. Epub 2008 Jul 25.
Chlorophylls are the most abundant tetrapyrrole molecules essential for photosynthesis in photosynthetic organisms. After many years of intensive research, most of the genes encoding the enzymes for the pathway have been identified, and recently the underlying molecular mechanisms have been elucidated. These studies revealed that the regulation of chlorophyll metabolism includes all levels of control to allow a balanced metabolic flow in response to external and endogenous factors and to ensure adaptation to varying needs of chlorophyll during plant development. Furthermore, identification of biosynthetic genes from various organisms and genetic analysis of functions of identified genes enables us to predict the evolutionary scenario of chlorophyll metabolism. In this review, based on recent findings, we discuss the regulation and evolution of chlorophyll metabolism.
叶绿素是光合生物光合作用所必需的最丰富的四吡咯分子。经过多年深入研究，该途径中编码酶的大多数基因已被鉴定出来，最近其潜在的分子机制也已阐明。这些研究表明，叶绿素代谢的调控涵盖了所有控制层面，以响应外部和内部因素实现平衡的代谢流，并确保在植物发育过程中适应叶绿素的不同需求。此外，从各种生物体中鉴定生物合成基因以及对已鉴定基因功能进行遗传分析，使我们能够预测叶绿素代谢的进化情况。在本综述中，基于最近的研究发现，我们讨论叶绿素代谢的调控与进化。
