Darien B J, Potempa J, Moore J N, Travis J
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824.
Equine Vet J. 1991 May;23(3):211-4. doi: 10.1111/j.2042-3306.1991.tb02758.x.
Antithrombin-III (AT-III) activity was measured at the time of admission in 46 horses referred with colic. Differences in AT-III activities between animals treated medically or surgically and survivors or non-survivors were compared. The mean AT-III values for the horses treated medically (76.2 per cent), surgical survivors (69.5 per cent) and surgical non-survivors (55.9 per cent) were significantly different from the reference value for healthy adults (92 to 108 per cent). The mean AT-III activity of the survivors was significantly (P less than 0.01) greater than that of the nonsurvivors. The majority of the survivors (11 to 13 horses) had AT-III activities exceeding 60 per cent of normal, whereas that of 10 of the 14 non-survivors was less than 60 per cent of normal. There was an apparent distinction between the survivors and non-survivors at approximately 60 per cent of normal AT-III activity.
对46匹因急腹症转诊的马匹在入院时测定了抗凝血酶III(AT-III)活性。比较了接受内科治疗或外科治疗的动物以及存活者或非存活者之间AT-III活性的差异。接受内科治疗的马匹(76.2%)、外科治疗存活者(69.5%)和外科治疗非存活者(55.9%)的平均AT-III值与健康成年马的参考值(92%至108%)有显著差异。存活者的平均AT-III活性显著(P小于0.01)高于非存活者。大多数存活者(11至13匹马)的AT-III活性超过正常的60%,而14例非存活者中有10例的AT-III活性低于正常的60%。在AT-III活性约为正常的60%时,存活者和非存活者之间存在明显差异。