Weir Robin A P, Martin Thomas N, Petrie Colin J, Murphy Aengus, Clements Suzanne, Steedman Tracey, Wagner Galen S, McMurray John J V, Dargie Henry J
Cardiology Department, Western Infirmary, Glasgow, UK.
Cardiology. 2009;113(1):1-8. doi: 10.1159/000161233. Epub 2008 Oct 10.
All patients should undergo formal assessment of ventricular function following acute myocardial infarction (AMI). Cardiac magnetic resonance (CMR) is not widely used as a test before discharge in AMI patients. This study sought to determine the impact of contrast-enhanced CMR (ceCMR) scanning before discharge in addition to standard transthoracic echocardiography (TTE) on patient care following AMI.
100 patients admitted with AMI, all of whom had a left ventricular ejection fraction (LVEF) <40% on TTE, underwent ceCMR imaging before discharge. Abnormalities of clinical relevance detected on ceCMR, which influenced patient management, are reported.
Each patient (77% male, mean age 58.9 years, SD 12) underwent TTE and ceCMR at a mean 1.4 (range 0.8-3.2) and 4.2 days (range 2-11), respectively, following admission. ceCMR significantly influenced the management of 24/100 (24%) of the patient cohort, through detection of LV thrombus, right ventricular infarction, intracardiac neoplasia, and a variety of intrathoracic and intra-abdominal pathology. There were no issues regarding safety in this high-risk group of patients.
In a cohort of AMI patients with reduced LVEF, ceCMR scanning before discharge improved the management of 24% of the cohort. ceCMR is a useful and safe adjunct to standard care after AMI.
所有急性心肌梗死(AMI)患者在发病后均应接受心室功能的正式评估。心脏磁共振成像(CMR)在AMI患者出院前作为一项检查尚未得到广泛应用。本研究旨在确定除标准经胸超声心动图(TTE)外,出院前行对比增强CMR(ceCMR)扫描对AMI患者后续治疗的影响。
100例因AMI入院的患者,所有患者TTE检查显示左心室射血分数(LVEF)<40%,在出院前接受ceCMR成像检查。报告ceCMR检查发现的影响患者治疗的具有临床意义的异常情况。
每位患者(男性占77%,平均年龄58.9岁,标准差12)入院后分别于平均1.4天(范围0.8 - 3.2天)和4.2天(范围2 - 11天)接受了TTE和ceCMR检查。ceCMR通过检测左心室血栓、右心室梗死、心内肿瘤以及各种胸内和腹内病变,显著影响了24/100(24%)患者队列的治疗。在这个高危患者群体中未出现安全性问题。
在LVEF降低的AMI患者队列中,出院前行ceCMR扫描改善了24%患者的治疗。ceCMR是AMI后标准治疗的一种有用且安全的辅助手段。