Sugai M, Ooku K, Akiyama T, Inoue S, Iseda S, Miyake Y, Suginaka H
Department of Microbiology, Hiroshima University School of Dentistry, Japan.
FEMS Microbiol Lett. 1991 May 15;64(2-3):151-4. doi: 10.1016/0378-1097(91)90586-y.
The effect of cibacron blue 3G-A (CB) on bacteriolysis induced by penicillin G was investigated using Staphylococcus aureus FDA 209P. Penicillin-induced lysis was completely inhibited by 30 microM CB. However, the bactericidal effect of penicillin G was not influenced by CB. These results indicate that a bacteriolytic process is not essential for penicillin to kill S. aureus.