窄带成像喉镜对咽部浅表癌早期检测的前瞻性研究
Prospective study of early detection of pharyngeal superficial carcinoma with the narrowband imaging laryngoscope.
作者信息
Ugumori Toru, Muto Manabu, Hayashi Ryuichi, Hayashi Tomomasa, Kishimoto Seiji
机构信息
Division of Head and Neck Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha Kashiwa-city, Chiba 277-8577, Japan.
出版信息
Head Neck. 2009 Feb;31(2):189-94. doi: 10.1002/hed.20943.
BACKGROUND
The newly developed narrowband imaging (NBI) gastrointestinal endoscope makes possible the detection of superficial carcinoma in the oropharynx and hypopharynx, which is difficult with the conventional laryngoscope. Here, we investigated whether the combined use of laryngoscope with NBI allows the detection of superficial carcinoma in this region.
METHODS
A total of 51 superficial, histologically confirmed lesions in 29 patients were studied. The quality of visualization of superficial carcinoma in the oropharynx and hypopharynx using the NBI-equipped laryngoscope was evaluated in comparison with the results by conventional laryngoscopy.
RESULTS
The NBI laryngoscope provided better detection of the irregular microvascular pattern of carcinoma than the conventional laryngoscope (p <.05) and better visualization of the demarcation line (p <.05), and thus significantly better visualization of the lesions.
CONCLUSION
The NBI laryngoscope may play an important role in the diagnosis and treatment of superficial carcinoma in the oropharynx and hypopharynx.
背景
新开发的窄带成像（NBI）胃肠内窥镜能够检测口咽和下咽的浅表癌，而传统喉镜很难做到这一点。在此，我们研究了喉镜与NBI联合使用是否能检测该区域的浅表癌。
方法
对29例患者共51处经组织学证实的浅表病变进行了研究。将配备NBI的喉镜用于口咽和下咽浅表癌的可视化质量与传统喉镜检查结果进行比较评估。
结果
与传统喉镜相比，NBI喉镜能更好地检测癌的不规则微血管形态（p <.05），并能更好地显示分界线（p <.05），从而能显著更好地显示病变。
结论
NBI喉镜可能在口咽和下咽浅表癌的诊断和治疗中发挥重要作用。
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