Dalal Aman, Ahmad Hameed
Division of Infectious Diseases, New York Hospital Queens, Flushing, New York 11355, USA.
Am J Med Sci. 2008 Oct;336(4):354-5. doi: 10.1097/MAJ.0b013e31815bd256.
This report describes a case of Austrian syndrome (pneumonia, meningitis, and endocarditis, as a result of Streptococcus pneumoniae infection). A computerized medline search was performed for review of literature. In the review of literature, 54 cases including our case were found. Complete clinical and microbiological information was available only for 20 cases. Most invasive pneumococcal infections occurred in debilitated middle aged men with chronic alcoholism. Native aortic valve insufficiency was the commonest cause of cardiac failure among these patients, requiring valve replacement. Austrian syndrome is seen infrequently in this antibiotic era but is still associated with a poor outcome. Hence early recognition and appropriate medical or combined medical-surgical treatment needs to be considered promptly.
本报告描述了一例奥地利综合征(由肺炎链球菌感染导致的肺炎、脑膜炎和心内膜炎)。通过计算机检索医学文献数据库以回顾相关文献。在文献回顾中,共发现包括我们的病例在内的54例病例。仅20例病例有完整的临床和微生物学信息。大多数侵袭性肺炎球菌感染发生在患有慢性酒精中毒的体弱中年男性中。在这些患者中,原发性主动脉瓣关闭不全是导致心力衰竭的最常见原因,需要进行瓣膜置换。在这个抗生素时代,奥地利综合征并不常见,但仍然与不良预后相关。因此,需要及时考虑早期识别以及适当的药物治疗或药物与手术联合治疗。